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The Renal Handling of Dextran 40 by Surgical Patients
Author(s) -
HEALE W. F.,
NIALL J. F.,
DOYLE J. C.
Publication year - 1968
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1971.tb05194.x
Subject(s) - medicine , dextran , renal function , urine , urine output , surgery , intensive care medicine , urology , chromatography , chemistry
A study has been made of the renal handling of low molecular weight dextran (dextran 40) by surgical patients. In spite of the usual fall in glomerular filtration rate during surgery, high urine dextran concentrations may occur, with the formatin of highly viscous urine. In view of the possible association between high dextron concentrations and oliguric renal failure, precautions in its administration are suggested with particular emphasis on the maintenance of urine flow rates.