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A Comparison of the Anticoagulant Effects of Heparin and Phenindione on a Standard Experimental Arterial Thrombus 1
Author(s) -
Hunt P. S.,
Reeve T. S.,
Hollings R. M.,
Sherwood R.,
Kearns R.
Publication year - 1969
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1969.tb05590.x
Subject(s) - medicine , thrombus , heparin , anticoagulant , cardiology
A standard experimental thrombus was produced electrically in the femoral arteries of sheep. The resultant clots were attacked with heparin or phenindione. Heparin prevented formation of the thrombus in test animals, and in animals with established thrombi it prevented further propagation. Phenindione was not successful in either of these roles.
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