Premium
The Effect of Oral Framycetin upon Colon Flora and upon Abscess Formation about Colon Wounds in Dogs
Author(s) -
Ryan Peter,
Stratford Bryan,
Dixson Shirley
Publication year - 1969
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1969.tb05570.x
Subject(s) - medicine , feces , flora (microbiology) , abscess , pouch , microbiology and biotechnology , bacteria , surgery , biology , genetics
During experiments designed to test the effect of bacterial contamination and infection upon the healing of colon wounds, fecal specimens removed directly from the dog's colon at colotomy have been examined microbiologically in one (“treated”) group after, and in another (“control”) group without, framycetin medication. The bacterial flora of the dog's colon were found to resemble those in the human colon, and as previously shown in human cases, framycetin completely eliminated coliform organisms from the feces. After closure of such a colotomy wound, an abscess almost always developed in the subcutaneous pouch in which it had been fixed, whether or not the dog had been “prepared” with framycetin, but fewer colonies of organisms grew from the abscesses found in the “prepared” cases, and pus from none of these latter abscesses grew Escherichia coli on culture .