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THE GENETIC APPROACH TO HEREDITARY CONGENITAL PTOSIS
Author(s) -
RANK B. K.,
THOMSON J. A.
Publication year - 1959
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1959.tb06969.x
Subject(s) - penetrance , medicine , ptosis , incidence (geometry) , significant difference , genetics , pediatrics , surgery , gene , biology , phenotype , physics , optics
Summary 1. It is considered that ptosis and ptosis with epicanthus are probably manifestations of the same dominant autosomal gene with high penetrance. 2. There is no significant difference in the proportion of affected males and females in sibships with one parent affected. The apparent difference in sex incidence of the condition is due to the high sex ratio observed in such sibships. 3. An appeal is made for the collection of unselected pedigree material for use in genetic studies.