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RHEUMATOID ARTHRITIS, LEG ULCERATION AND POSITIVE LUPUS ERYTHEMATOSUS CELL TEST
Author(s) -
Benjamin M. K.,
Hueston J. T.
Publication year - 1959
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1959.tb03827.x
Subject(s) - medicine , rheumatoid arthritis , cortisone , arthritis , dermatology , pathogenesis , immune system , surgery , immunology
Summary1 A report is given of an elderly male with rheumatoid arthritis, chronic ulceration of the leg and positive L.E. cell test, as described by Allison and Bettley (1957). In addition the auto‐immune complement fixation (AICF) test was positive. 2 Split skin autografts to the ulcer failed, to survive. When repeated during continuing cortisone administration they survived. 3 This experience favours an immunological I pathogenesis both for the original ulcer and for the non‐survival of the initial autograft. 4 A plan is submitted for the investigation of cases with rheumatoid arthritis and leg ulceration including an L.E. cell test. Treatment of such cases is suggested based on the use of cortisone if an initial graft fails to survive.