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SARCOMA OF PERIPHERAL NERVES.
Author(s) -
Dew Harold R.
Publication year - 1935
Publication title -
australian and new zealand journal of surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 51
eISSN - 1445-2197
pISSN - 0004-8682
DOI - 10.1111/j.1445-2197.1935.tb02655.x
Subject(s) - medicine , sarcoma , amputation , malignancy , disease , limiting , surgery , pathology , mechanical engineering , engineering
Summary 1. Neurogenic sarcoma may occur in the larger peripheral nerve trunks as a primary solitary neoplasm, or secondary to a primary neuro‐fibroma, in which case other manifestations of this disease should be 2. This tumour is a very treacherous one, of varying degrees of malignancy, but extremely prone to recurrence and finally t o cause death from pulmonary metastases. A study of many recorded cases shows that the prognosis after conservative measures is extremely gloomy, the mortality approaching that of bone sarcoma. 3. If operation is undertaken it should be radical; no conservative measures are of any avail, and, if recurrence, which is very common, takes place, amputation holds out the only chance of saving life. 4. Operative interference with slowly growing nerve tumours with few symptoms should not be lightly undertaken, owing t o the risk of inducing sarcomatous change. 5. Deep X ray therapy has a very limited and rather disappointing effect on most of these neoplasms, but the consensus of opinion is that with a view t o limiting recurrence, it should be used intensively as soon after operation as possible.