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Lymphadenopathy, elevated liver function tests and weight loss in a 68‐year‐old man
Author(s) -
KROK Karen L,
TORBENSON Micheal S,
SCHULICK Richard D,
THULUVATH Paul J
Publication year - 2007
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/j.1443-9573.2007.00294.x
Subject(s) - medicine , histiocyte , liver biopsy , presentation (obstetrics) , weight loss , liver function tests , phagocytosis , pathology , elevated liver enzymes , biopsy , liver function , immunostaining , radiology , gastroenterology , immunohistochemistry , immunology , pregnancy , genetics , biology , obesity
A 68‐year‐old man presented to the hospital with fevers, weight loss, lymphadenopathy and abnormal liver‐associated enzymes. After a thorough workup, a liver biopsy demonstrated histiocytes with phagocytosis of the lymphocytes and a positive immunostain for S‐100. The diagnosis of Rosai‐Dorfman disease was made. This case report will discuss the patient's presentation as well as the diagnosis and treatment of this rare, non‐malignant disorder, which only rarely affects the liver.