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Efficacy and safety of a W all F lex enteral stent for malignant gastric obstruction
Author(s) -
Kanno Yoshihide,
Ito Kei,
Fujita Naotaka,
Noda Yutaka,
Kobayashi Go,
Horaguchi Jun,
Koshita Shinsuke,
Ogawa Takahisa,
Masu Kaori,
Hirasawa Dai,
Sugawara Toshiki,
Koike Yoshiki,
Hashimoto Shinichi,
Ishii Syoutarou
Publication year - 2013
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2012.01396.x
Subject(s) - medicine , gastric outlet obstruction , enteral administration , stent , feeding tube , perforation , surgery , confidence interval , pancreatitis , clinical efficacy , parenteral nutrition , gastroenterology , punching , materials science , metallurgy
Aim The aim of the present study was to investigate the efficacy and safety of a newly available enteral W all F lex stent for malignant gastric outlet obstruction ( GOO ). Methods Twenty‐one consecutive patients with symptomatic (unable to take solids) malignant GOO treated by a W all F lex stent from A pril 2010 to F ebruary 2012 were included and analyzed retrospectively. Main outcome measurements were technical success, early complications, clinical response (elimination of the need for nasogastric tube drainage), clinical success (improvement of oral intake to a GOO score of 2 or 3), and duration of sustaining a GOO score of 2 or 3 after clinical success (median duration until reworsening of GOO score to <2 by the K aplan– M eier method). A four‐point GOO scoring system (0–3) was used for estimation of oral intake. Results Technical success rate was 100%. Bleeding and perforation after stent placement and stent dislocation/migration in the follow‐up period did not occur in any patients, whereas one patient (5%) developed moderate post‐procedural pancreatitis. Clinical response and clinical success was achieved in all patients and in 81% (17/21), respectively. In 17 patients whose GOO score had improved to 2 or 3 after stent placement, eight (47%) developed reworsening of the GOO score to <2 with a median time of 148 days (95% confidence interval [ CI ], 0–328; K aplan– M eier method). Median survival time after the initial intervention was 61 days (95% CI , 40–82). Conclusion Placement of an enteral W all F lex stent in patients with malignant GOO is safe and effective.