Premium
Carbon dioxide insufflation safety in double‐balloon enteroscopy: An experimental animal study
Author(s) -
Soria Federico,
LopezAlbors Octavio,
Morcillo Esther,
Martin Carolina,
Sarria Ricardo,
Esteban Pilar,
Carballo Fernando,
PerezCuadrado Enrique,
Sanchez Francisco M,
Latorre Rafael
Publication year - 2013
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2012.01320.x
Subject(s) - insufflation , medicine , hemodynamics , anesthesia , arterial blood , enteroscopy , room air distribution , balloon , carbon dioxide , double balloon enteroscopy , endoscopy , surgery , chemistry , physics , organic chemistry , thermodynamics
Aim The aim of the present study was to assess the safety and efficacy of CO 2 during double‐balloon enteroscopy ( DBE ) in an experimental animal model study. In this study, insufflation with room air and with CO 2 was compared. Methods Twenty healthy swines were used. The animals were randomly allocated to two groups. The room air‐ DBE group was insufflated with room air, whereas the CO 2 ‐ DBE group was insufflated with CO 2 . Endoscopy duration was 90 min. The following parameters were measured during the study (basal, 30 min, 60 min, 90 min): invasive hemodynamic parameters, ventilatory parameters, arterial blood gases, exploration depth, as well as biochemical tests. Residual gas was evaluated at the end of DBE , at 180 min and 24 h after DBE . Results During the endoscopic exploration none of the animals showed hemodynamic, ventilatory or arterial blood gas alterations in the normal reference range for the swine species. The CO 2 group showed statistically significant differences over the room air group with lower post‐procedure residual gas and greater depth of the small bowel explored. Conclusion The use of CO 2 for insufflation during DBE was safe and no complications associated with CO 2 were observed. In addition, the use of CO 2 offers benefits over the use of room air for insufflation during DBE .