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The efficacy of transcatheter arterial embolization as the first‐choice treatment after failure of endoscopic hemostasis and endoscopic treatment resistance factors
Author(s) -
Katano Takahito,
Mizoshita Tsutomu,
Senoo Kyoji,
Sobue Satoshi,
Takada Hiroki,
Sakamoto Tomoyuki,
Mochiduki Hisato,
Ozeki Takanori,
Kato Akihisa,
Matsunami Kayoko,
Ito Kazuyuki,
Joh Takashi
Publication year - 2012
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2012.01285.x
Subject(s) - medicine , hemostasis , surgery , arterial embolization , perforation , embolization , endoscopy , retrospective cohort study , punching , materials science , metallurgy
Aim: The aim of this retrospective study was to evaluate the efficacy of transcatheter arterial embolization (TAE) as the first‐choice treatment in patients with bleeding peptic ulcer after the failure of endoscopic hemostasis. An additional objective was to clarify endoscopic treatment resistance factors. Methods: Between April 2004 and December 2010, 554 patients were admitted to Kasugai Municipal Hospital for necessary endoscopic hemostasis for bleeding gastric ulcer or duodenal ulcer. In the patients for whom endoscopic hemostasis failed, TAE was attempted. If TAE failed, the patients underwent surgery. The backgrounds of the patients in whom endoscopic treatment was successful and in whom it failed were compared. Results: TAE was attempted in 15 patients (2.7%). In 12 (80.0%) of 15 patients, embolization with coils was successful. In one patient (6.7%), embolization was ineffective. This patient underwent emergent salvage surgery. In two (13.3%) of 15 patients, no extravasation was observed during arteriography. These patients were cured with medication. In two patients, ulcer perforation was observed during endoscopy after rebleeding. These patients underwent surgery. In total, 3 (0.5%) of 554 patients underwent surgery. No recurrent bleeding was observed after TAE. Hemoglobin level <8 g/dL at presentation ( P = 0.02), Rockall score ≥7 at presentation ( P = 0.002), and Forrest class Ia/Ib at initial endoscopic hemostasis ( P < 0.001) were found to be independent significant endoscopic treatment resistance factors. Conclusions: TAE is a safe and effective first‐choice treatment for patients in whom endoscopic hemostasis has failed.