Premium
LOCAL RECURRENCE AND SURVEILLANCE AFTER ENDOSCOPIC RESECTION OF LARGE COLORECTAL TUMORS
Author(s) -
Hotta Kinichi,
Saito Yutaka,
Matsuda Takahisa,
Shinohara Tomoaki,
Oyama Tsuneo
Publication year - 2010
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2010.00965.x
Subject(s) - medicine , endoscopic submucosal dissection , perforation , surgery , endoscopic mucosal resection , resection , confidence interval , retrospective cohort study , endoscopy , dissection (medical) , radiology , materials science , punching , metallurgy
Local recurrence rates after endoscopic piecemeal mucosal resection (EPMR) typically range from 10 to 23%. In our previous study, the local recurrence rate after a piecemeal resection was significantly higher than that after an en bloc resection, irrespective of tumor size or macroscopic features. To reduce local recurrence after an EPMR, it is important to carefully note the circumferences of the edge and base of the ulcer. Recently, endoscopic submucosal dissection (ESD) was developed and recognized for its effectiveness in large, complete, en bloc resections and precise pathological assessments. ESD also showed lower local recurrence rates, ranging from 0 to 3% in previous, retrospective studies. However, ESD showed a higher perforation rate and longer procedure times; thus, it is necessary to improve ESD. An appropriate surveillance interval after EPMR was still controversial, and recommendations of some guidelines ranged from 2 to 9 months. In order to determine the appropriate interval, a randomized controlled study is necessary.