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ENDOMETRIOID ADENOCARCINOMA ARISING FROM ENDOMETRIOSIS OF THE RECTOSIGMOID
Author(s) -
Kobayashi Shigeru,
Sasaki Morio,
Goto Tatsuya,
Asakage Naoki,
Sekine Masayuki,
Suzuki Takahisa,
Tsukada Kenji,
Yamasaki Shigetaka,
Ukawa Shiro
Publication year - 2010
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2009.00925.x
Subject(s) - medicine , endometriosis , rectum , carboplatin , adenocarcinoma , chemotherapy , complication , oncology , cancer , cisplatin
A case of endometrioid adenocarcinoma supposedly arising from endometriosis of the rectum is reported. Malignant transformation is uncommon but a well‐known complication of endometriosis. In the present case, it was proved by histopathological findings and immunophenotype such as cytokeratin7+/cytokeratin20−/estrogen receptor+. The cause of rectal endometriosis in this case might have been related with previously received hormone replacement therapy for ovarian endometriosis. Following surgical removal of the lesion, this patient underwent adjuvant chemotherapy with paclitaxel and carboplatin, although this kind of therapy is still controversial as to its effectiveness.