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SMALL BOWEL PSEUDOMELANOSIS AND ORAL IRON THERAPY
Author(s) -
Almeida Nuno,
Figueiredo Pedro,
Lopes Sandra,
Freire Paulo,
Sousa Vítor,
Lérias Clotilde,
Gouveia Hermano,
Leitão Maximino C.
Publication year - 2009
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2009.00834.x
Subject(s) - enteroscopy , medicine , lamina propria , capsule endoscopy , iron deficiency anemia , gastroenterology , double balloon enteroscopy , anemia , oral mucosa , endoscopy , pathology , epithelium
Small bowel pseudomelanosis is a rarely reported clinical entity characterized by brown pigmentation of small bowel mucosa. The authors describe two cases, both with iron deficiency anemia, one of an 81‐year‐old female patient submitted for capsule endoscopy that revealed a brown pigmentation of all small bowel mucosa and another of an 81‐year‐old male whose retrograde double‐balloon enteroscopy revealed a diffuse brown pattern of small bowel mucosa. Ileal biopsies confirmed intense iron deposition in the macrophages of the lamina propria. Both patients were on oral iron therapy and the second one had a previous double‐balloon enteroscopy, 2 years earlier, which revealed only ileal angiodysplasias. These two cases demonstrate the importance of two new endoscopic methods for diagnosis of small bowel pseudomelanosis, the rarity of such an entity and its close relation with oral iron therapy.