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SURVEILLANCE FOR DYSPLASIA AND COLITIC CANCER BY MAGNIFYING COLONOSCOPY IN PATIENTS WITH ULCERATIVE COLITIS
Author(s) -
Kobayashi Kiyonori,
Igarashi Masahiro,
Sada Miwa,
Katsumata Tomoe,
Saigenji Katsunori
Publication year - 2005
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2005.00530.x
Subject(s) - medicine , ulcerative colitis , colonoscopy , dysplasia , colorectal cancer , cancer , gastroenterology , biopsy , pathology , disease
The aim of this study was to evaluate the macroscopic appearance and pit pattern of colitic cancer and dysplasia associated with ulcerative colitis (UC) by conventional and magnifying colonoscopy. Twelve lesions of dysplasia in nine patients and five colitic cancers in four patients were observed by magnifying colonoscopy. On conventional colonoscopy, most colitic cancers and dysplasias were protruded lesions. However, flat lesions were observed only in dysplasia, not in colitic cancer. All colitic cancers and 83% (10/12 lesions) of dysplasias presented reddish surface. On magnifying colonoscopy, most lesions of colitic cancer and dysplasia showed III S to III L or III L to IV or IV type pit patterns. Tumorous pits associated with colitic cancers and dysplasias were similar to those seen in sporadic colorectal cancers and adenomas. Magnifying colonoscopy is expected to facilitate the qualitative diagnosis of colitic cancer and dysplasia associated with ulcerative colitis and to improve the efficiency of targeted biopsy.