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DAI‐KENCHU‐TO, A HERBAL MEDICINE, IMPROVES PRECOLONOSCOPY BOWEL PREPARATION WITH POLYETHYLENE GLYCOL ELECTROLYTE LAVAGE: RESULTS OF A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL
Author(s) -
Saida Yoshihisa,
Sumiyama Yoshinobu,
Nagao Jiro,
Nakamura Yasushi,
Nakamura Yoichi,
Katagiri Miwa
Publication year - 2005
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2005.00428.x
Subject(s) - medicine , nausea , colonoscopy , bowel preparation , abdominal pain , randomized controlled trial , group b , peg ratio , gastroenterology , prospective cohort study , cecum , group a , polyethylene glycol , surgery , colorectal cancer , finance , cancer , chemical engineering , engineering , economics
Background: This prospective randomized controlled trial examines the effect of combination of Dai‐kenchu‐to (DKT), a traditional Japanese herbal medicine, and polyethylene glycol electrolyte (PEG) lavage in precolonoscopic preparation. Methods: Two hundred and eight‐five colonoscopy patients from January to December 2001 were divided into two groups randomly; 144 patients into group A (with DKT) and 141 into group B (without DKT). Results: Abdominal pain and nausea were observed in 17% and 24% of group A, and 15% and 21% of group B, respectively. Preparation scores were 0.28 ± 0.52 in group A and 0.81 ± 0.77 in group B. Times for reaching the cecum were 6.4 ± 3.6 min in group A and 7.3 ± 4.0 min in group B. Group A demonstrated significantly better preparation ( P < 0.001) and shorter times ( P = 0.04) than group B. Conclusion: The present study indicates that DKT in combination with PEG is a safe and gentle method, improving precolonoscopic bowel preparation without increasing abdominal pain and nausea.