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THE HEALING PROCESS OF GASTRIC ARTIFICIAL ULCERS AFTER ENDOSCOPIC SUBMUCOSAL DISSECTION
Author(s) -
Kakushima Naomi,
Yahagi Naohisa,
Fujishiro Mitsuhiro,
Iguchi Mikitaka,
Oka Masashi,
Kobayashi Katsuya,
Hashimoto Takuhei,
Omata Masao
Publication year - 2004
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2004.00413.x
Subject(s) - medicine , endoscopic submucosal dissection , sucralfate , peptic , endoscopy , surgery , endoscopic mucosal resection , endoscopic treatment , wound healing , peptic ulcer , gastroenterology
Background: Due to the remarkable progress of endoscopic resection techniques, endoscopic submucosal dissection (ESD) has been widely performed for larger mucosal tumors that would result in large articial ulcers. The healing process of peptic ulcers has been previously studied in detail; however, no precise investigation for articial ulcers after ESD has been reported. To conrm the validity of the treatment from the aspect of wound healing, we aimed to clarify the healing process of large gastric articial ulcers after ESD. Methods: Seventy patients with gastric mucosal tumors treated by ESD were enrolled. The size, location and time of scar formation of the ulcers were reviewed using endoscopic pictures taken from the same view and angle. Follow‐up endoscopy was performed at 1, 4, 8 and 12 weeks after ESD. For postoperative medication, all patients received normal doses of proton pump inhibitors and sucralfate for 8 weeks. Results: The average size of the resected specimen was 34.7 mm (20–90 mm). Irrespective of ulcer size and location, all of the cases healed up to scarring stages within 8 weeks. Conclusions: Gastric articial ulcers after ESD healed within 8 weeks regardless of size and location using normal doses of medication as peptic ulcers. The fact that even giant ulcers after ESD heal within 8 weeks could be helpful information for candidates for ESD and for postoperative management of patients after ESD.