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Autoimmune pancreatitis associated with biliary stricture, immune thrombocytopenic purpura and lung fibrosis
Author(s) -
Nakazawa Takahiro,
Kobayashi Kunio,
Ohara Hirotaka,
Sano Hitoshi,
Ando Tomoaki,
Yamada Tamaki,
Nomura Tomoyuki,
Joh Takashi,
Itoh Makoto
Publication year - 2004
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.2004.00357.x
Subject(s) - medicine , autoimmune pancreatitis , thrombocytopenic purpura , bile duct , anti nuclear antibody , pancreatitis , intrahepatic bile ducts , gastroenterology , pathology , radiology , immune system , antibody , autoantibody , immunology
We report an autoimmune pancreatitis case with diverse manifestation of biliary stricture, lung brosis and immune thrombocytopenic purpura. The patient was a 70‐year‐old man who presented with jaundice. Abdominal ultrasonography and computed tomography revealed enlargement of the entire pancreas and endoscopic retrograde pancreatography showed diffuse irregular narrowing of the main pancreatic duct. Endoscopic retrograde cholangiography revealed a band‐like stricture of the bile duct in the hilar hepatic region with intrahepatic duct dilation. Chest X‐rays and computed tomography revealed interstitial brosis of the bilateral lower lungs. Thrombocytopenia and purpura appeared. Antinuclear antibody, anti‐Ro (SS‐A) and anti‐La (SS‐B) antibodies and rheumatoid factor were positive. All manifestations responded well to steroid therapy. From the present case it would appear that a multitude of manifestations are linked within one syndrome. If we encounter patients with autoimmune pancreatitis, we should not focus on a disease but rather on the possibility of a syndrome complex.