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Laparoscopic Findings in Primary Sclerosing Cholangitis
Author(s) -
KOMATSU Masafumi,
HOSHINO Takao,
ONO Tsuyoshi,
GOTO Takashi,
OHSHIMA Shigetoshi,
YONEYAMA Kazuo,
FUJII Tomoo,
KURAMITSU Tomoyuki,
NAKANE Kunio,
MIKAMI Kenichiro,
YAGISAWA Hitoshi,
MASAMUNE Osamu
Publication year - 1999
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1999.tb00189.x
Subject(s) - medicine , primary sclerosing cholangitis , cholestasis , primary biliary cirrhosis , fibrosis , cirrhosis , intrahepatic bile ducts , gastroenterology , pathology , bile duct , disease
The laparoscopic appearance of the liver surface in patients with primary sclerosing cholangitis (PSC) has not been fully delineated. We examined 5 patients with PSC and reviewed 35 previously reported cases. Intense white markings in a mesh‐like pattern were characteristic of PSC. The findings varied depending on the histologic stage and affected site. Red patches which have also been seen in primary biliary cirrhosis (PBC), green patches indicating cholestasis, and dilatation of the terminal bile ducts were also observed. The red patches were wider than those in PBC. The white markings were less well defined in the red patches than in other areas. The severity of the fibrosis and histologic damage was judged to be mild at the red sites. The green patches were caused by localized cholestasis. This indicated that PSC unevenly affects the liver. Severe obstruction may be present between the interlobular bile ducts and the septal bile ducts in anicteric stages. (Dig Endosc 1999; 10: 37–41)