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A Huge Polypoid Type Early Gastric Neuroendocrine Cell Carcinoma
Author(s) -
KUSAKA Toshihiro,
SANO Yasushi,
ARAO Jun,
ICHIKAWA Kazuhito,
YamamuraIDEI Yuka,
SHIMIZU Shinichi,
TSUCHIYA Kazuhiro,
UEDA Yoshihiko,
CHIBA Tsutomu,
FUJIMORI Takahiro
Publication year - 1998
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1998.tb00565.x
Subject(s) - medicine , adenocarcinoma , pathology , neuroendocrine tumors , gastrectomy , enteroendocrine cell , neuroendocrine differentiation , endocrine system , lesion , cancer , medullary cavity , carcinoma , multiple endocrine neoplasia , gastroenterology , biology , hormone , biochemistry , prostate cancer , gene
We report a case of a huge polypoid‐type early gastric neuroendocrine cell carcinoma. Upper gastrointestinal endoscopy in a 77‐year‐old man revealed a gastric polyp on the anterior wall of the corpus. Endoscopically biopsied material from the polyp suggested that the lesion was malignant; specifically a poorly and moderately differentiated tubular adenocarcinoma or adenocarcinoma with neuroendocrine differentiation. Endoscopically the lesion was a huge polypoid type with a broad stalk approximately 40 mm in diameter, and its surface was tabulated with a white coat and erosion. The patient underwent total gastrectomy. The resected specimen histopathologically showed a polypoid mass with medullary carcinoma and indicated endocrine cell differentiation. Immunohis‐tochemical findings supported the diagnosis of endocrine cell carcinoma. This case was an early and polypoid‐type gastric endocrine cell carcinoma. Since examples of such cases are rare in the literature, we report this case in brief.