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Primary Gastric Carcinoma with the Bull's eye Sign in a Case of Breast Cancer — Immunohistochemical Differentiation from Metastatic Cancer—
Author(s) -
KISHI Hisayo,
IKEDA Masahiro,
MURAI Masami,
MASUZAWA Manabu,
KURATA Akihiko,
ARIMA Ryouichi
Publication year - 1993
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1993.tb00648.x
Subject(s) - medicine , immunohistochemistry , cancer , breast cancer , pathology , adenocarcinoma , carcinoma , biopsy , metastatic breast cancer , ca15 3 , primary tumor , metastatic carcinoma , oncology , metastasis
A 53‐year‐old female, who had undergone a mastectomy for breast cancer 4 years previously, was found to have gastric cancer. Judging from the Bull's eye sign of the upper GI series and endoscopy, it appeared to be a metastatic gastric cancer. Histopathological findings of biopsy specimens revealed adenocarcinoma and metastases from the breast cancer were not negligible. However, the surgically resected specimen had different immunohistochemical staining for CEA, Alcian blue, 115D8, and C‐erb B2 from the breast cancer. The tumor was finally diagnosed as a primary gastric carcinoma. This case shows that immunohistochemical studies are useful for differentiation between metastatic and primary gastric cancer