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A Case of Duodenal Crohn's Disease Associated with Ampullar Insufficiency and Cholangitis
Author(s) -
KATO Masahiko,
NINOMIYA Mitsuo,
SUGIURA Junsaku,
KATO Tomohiro,
SAITO Koshiro,
MORIWAKI Hisataka,
TOMITA Eiichi,
MUTO Yasutoshi,
OHSHIMA Kenjiro,
TAKAI Tetsu,
IKEDA Yoko,
SHIMOKAWA Kuniyasu
Publication year - 1992
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1992.tb00244.x
Subject(s) - medicine , major duodenal papilla , sphincter of oddi , gastroenterology , duodenum , stenosis , reflux , disease , crohn's disease , duodenal stenosis
A 67‐year‐old Japanese woman with duodenal Crohn's disease developed cholangitis. Radiographic and endoscopic examinations revealed a marked stenosis of the third portion and a dilatation of the second portion of the duodenum. The endoscopic and histopathological observations showed this disease affected the Vater's papilla. Duodenoscopic manometry indicated a reduced pressure of the phasic sphincter of Oddi, indicating ampullar insufficiency. E. coli was found in the bile culture as the infecting organism. The authors suggest that the cholangitis in this patient was caused by the reflux of duodenal contents into the biliary tract.