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Mucin Secreting Cholangiocarcinoma Associated with Clonorchiasis
Author(s) -
Hsu Ronald KK,
Lai Chiwai,
Lo Kikam,
Leung Joseph WC
Publication year - 1992
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1992.tb00114.x
Subject(s) - clonorchiasis , medicine , mucin , mucus , gastroenterology , obstructive jaundice , stent , pathology , immunology , biology , ecology , helminths
Hepatic clonorchiasis is implicated in the pathogenesis of mucin secreting cholangiocarcinoma in the Far East. Obstructive jaundice is often associated with the malignant stricture. We present a case with recurrent cholangitis due to biliary obstruction caused by excessive mucus produced by the tumor. The excess mucus and infected bile led to early stent clogging within a few weeks after stent insertion. Intraductal 5‐fluorouracil treatment resulted in an apparent reduction in mucus production. Apart from frequent admission for stent exchange, the patient has lived a reasonably good quality life for three years.