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Endoscopic Sclerotherapy for Esophageal Varices after Renal Transplantation: Report of One Autopsy Case
Author(s) -
SHIBUYA Susumu,
TAKASE Yasuhiro,
AOYAGI Hiroyuki,
CHIKAMORI Fumio,
SHARMA Niranjan,
KAWASHIMA Takahiko,
IWASAKI Yoji
Publication year - 1991
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1991.tb00267.x
Subject(s) - medicine , sclerotherapy , esophageal varices , varices , esophagus , gastric varices , transplantation , varix , surgery , radiology , portal hypertension , cirrhosis
Endoscopic sclerotherapy has been used to manage esophageal varices. Severe complications resulting from this therapy including renal dysfunction have been reported. Therefore, particular caution must be taken with patients who have serious renal damage. Sclerotherapy was performed for esophagogastric varices in a patient that had received a kidney transplant following chronic renal dysfunction. Ethanolamine oleate was used as the sclerosant, and contained a contrast medium for varicealography in order that the flow of the sclerosant be monitored by fluoroscopy. Varicography during the injection allowed us to stop injection into the varices and into the irregular passageways of the feeders to the varices before the agent entered the systemic circulation. There were no complications during therapy. The patient died due to respiratory failure 41 months after the first treatment. Macroscopic findings of the autopsied specimens showed no esophagogastric varices and microscopic findings showed organized varices with recanalization into the submucosal layer of the esophagogastric lesions. Injection sclerotherapy using varicography with sclerosant‐contrast medium mixture allowed treatment of this patient without incurring renal dysfunction.