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The pH Measurement of Fasting Gastric Juice in Acute Gastric Mucosal Lesions
Author(s) -
ITO Go,
KANEKO Eizo,
SAKAKIBARA Terue,
TAKEUCHI Yasushi,
KITAHARA Hirofumi,
KOBASHI Hiroshi,
ARAKI Atsushi,
TOKUNAGA Tadashi,
HASEGAWA Jun,
KOBAYASHI Nagaharu,
INOUE Kiyoshi
Publication year - 1989
Publication title -
digestive endoscopy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.5
H-Index - 56
eISSN - 1443-1661
pISSN - 0915-5635
DOI - 10.1111/j.1443-1661.1989.tb00032.x
Subject(s) - medicine , gastroenterology , stage (stratigraphy) , ph meter , chemistry , paleontology , biology
Fasting gastric juice acidity was assessed to elucidate its role in the cause of acute gastric mucosal lesions (AGML). Gastric juice was aspirated through an auxiliary endoscopic channel during routine endoscopic examinations, and its pH was measured with a glass electrode PH meter. The pH of 100 cases with AGML (acute hemorrhagic erosions (AHE), acute gastric ulcer and acute hemorrhagic gastritis), and 586 cases with other ulcerative or inflammatory lesions were compared with the gastric juice pH in 1775 endoscopically normal subjects. The pH value was classgied into four acid groups: Hyperacidity (pH < 1.4), Normoacidity (1).5 < pH < 2.0), Hypoacidity (2).1 < pH <4.0) and Anacidity (4). 1 < pH). In cases with AHE, a signifcant hyperacidity was recognized both in the periods preceding and just after the onset. This hyperacidity was followed by signgicant anacidity, and thereafter a return to normoacidity. These pH changes coincided well with endoscopic appearances; preceding stage‐hypernormacidity, black‐slough stage—hyperacidity, white‐slough stage‐anacidity and scarring stage‐;normoacidity. These results suggest that an elevation of gastric acidity etiologically relates with the formation of AGML, especially Shin.