Premium
Optometry‐based general population survey of pupil ruff atrophy and ocular hypertension
Author(s) -
Ang Ghee S,
Stevenson Peter J,
Sargent Geoff,
Grimmer Peter,
Corbett Patricia,
Jourdain Erin,
Wells Anthony P
Publication year - 2012
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/j.1442-9071.2012.02874.x
Subject(s) - medicine , intraocular pressure , ophthalmology , glaucoma , trabecular meshwork , gonioscopy , pseudoexfoliation syndrome , pupil , population , pseudoexfoliation , optometry , environmental health , neuroscience , biology
Background To evaluate and describe the pupil ruff changes and relationship to intraocular pressure, pseudoexfoliation syndrome and glaucoma status in an optometric population in N ew Z ealand. Design Prospective cross‐sectional survey of an optometric population. Participants Six hundred and twenty subjects over 50 years old routinely attending the participating optometry practices. Exclusion criteria included previous intraocular surgery, ophthalmic laser, uveitis, angle closure and secondary glaucoma. Methods Multicentre study involving 11 optometry practices in the Wellington region, N ew Z ealand. The pupillary ruff and associated gonioscopy findings of study participants were graded based on the previously published P upil R uff A trophy grading system. Parameters evaluated include pupillary ruff absence and abnormality, pseudoexfoliation material and trabecular meshwork pigmentation. Main Outcome Measures Correlations between intereye P upil R uff A trophy grading differences and inter‐eye intraocular pressure and cup:disc ratio differences. Results Six hundred and twenty subjects were included, with a mean age of 62.2 ± 9.1 years and mean intraocular pressure of 14.8 ± 3.4 mmHg . Four hundred and fourteen (66.8%) had bilateral pupil ruff changes and 12 (1.5%) had pseudoexfoliation. Inter‐eye intraocular pressure asymmetry was significantly correlated with amount of missing pupillary ruff (r = 0.111; P = 0.022) and trabecular meshwork pigmentation (r = 0.147; P = 0.002). Inter‐eye cup:disc ratio asymmetry was not correlated with any of the P upil R uff A trophy grading parameters. Conclusions Asymmetry of pupillary ruff absence and trabecular meshwork pigmentation was correlated with intraocular pressure asymmetry (but not with cup:disc ratio asymmetry) in a general optometric population setting in N ew Z ealand.