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Efficacy of wide‐field digital retinal imaging for retinopathy of prematurity screening
Author(s) -
Dai Shuan,
Chow Kent,
Vincent Andrea
Publication year - 2010
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/j.1442-9071.2010.02399.x
Subject(s) - retinopathy of prematurity , medicine , ophthalmoscopy , retinopathy , retinal , ophthalmology , neonatal intensive care unit , gestational age , pediatrics , pregnancy , genetics , endocrinology , biology , diabetes mellitus
A bstract Background: To evaluate the efficacy of wide‐field digital retinal imaging for retinopathy of prematurity screening. Design: Retrospective study in a quaternary public neonatal intensive care unit. Participants: A total of 108 premature infants screened for retinopathy of prematurity. Methods: Retrospective chart and photo review were performed on participants screened by both serial wide‐field digital retinal imaging and concurrent binocular indirect ophthalmoscopy. Review of captured digital photos was performed independently by a masked reader. Using the binocular indirect ophthalmoscopy findings as the gold standard, the efficacy of wide‐field digital retinal imaging in detecting treatment‐requiring retinopathy of prematurity, defined as type 1 prethreshold disease, was determined. Main Outcome Measures: Sensitivity and specificity of wide‐field digital retinal imaging in detecting treatment‐requiring retinopathy of prematurity. Results: Treatment‐requiring retinopathy of prematurity was detected in 11 infants by both binocular indirect ophthalmoscopy examination and telemedicine images taken at the same visit. Wide‐field digital retinal imaging has a sensitivity of 100% (95% CI: 76.2–100%) and a specificity of 97.9% (95% CI: 93.4–99.7%) in detecting infants with treatment‐requiring retinopathy of prematurity. Positive and negative predictive values of wide‐field digital retinal imaging were 84.6% (95% CI: 57.8–97.3%) and 100% (95% CI: 96.9–100%), respectively. Conclusions: Wide‐field digital retinal imaging is accurate, reliable and efficient in detecting treatment‐requiring retinopathy of prematurity. Incorporating wide‐field digital retinal imaging with telemedicine in standard retinopathy of prematurity management can potentially improve delivery, accessibility, quality and cost of retinopathy of prematurity care.