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Pseudoexfoliation syndrome: in vivo confocal microscopy analysis
Author(s) -
Martone Gianluca,
Casprini Fabrizio,
Traversi Claudio,
Lepri Francesca,
Pichierri Patrizia,
Caporossi Aldo
Publication year - 2007
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/j.1442-9071.2007.01535.x
Subject(s) - confocal microscopy , pleomorphism (cytology) , confocal , pathology , medicine , cornea , in vivo , microscopy , pseudoexfoliation syndrome , ophthalmology , biology , microbiology and biotechnology , optics , immunohistochemistry , physics , alternative medicine
A bstract Pseudoexfoliation (PEX) syndrome is a common ocular disease that also affects the cornea. A case of clinical PEX syndrome, studied by in vivo corneal confocal microscopy is reported. The morphological analysis of the confocal images demonstrated hyper‐reflective deposits and several dendritic cells in the basal epithelial layer. A fibrillar subepithelial structure was also found. The endothelial layer showed cell anomalies (polymegathism and pleomorphism) and hyper‐reflective small endothelial deposits. Confocal microscopy is an in vivo imaging method that may provide new information on corneal alterations in PEX, and detect early corneal features.