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Late‐onset post‐traumatic Phaeoacremonium parasiticum endophthalmitis
Author(s) -
Huynh Tu Khai,
Lee Lawrence R,
Ellis David
Publication year - 2007
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/j.1442-9071.2007.01486.x
Subject(s) - medicine , voriconazole , endophthalmitis , amphotericin b , scleritis , enucleation , surgery , dermatology , antifungal , ophthalmology , uveitis
A bstract This is the first documented case of Phaeoacremonium parasiticum endophthalmitis to the authors' knowledge. P. parasiticum has been described in the literature causing various skin, subcutaneous and joint infections and one case of infective endocarditis, but has never been documented as an ocular infectious agent. The most likely source of inoculation in this case was a penetrating injury caused by a stick 5 years prior to the presentation. An enucleation was avoided through treatment with intravitreal antibiotics and amphotericin and oral voriconazole, and the patient's vision stabilized at 6/18. Microbiological studies were delayed but confirmed the mould's sensitivity to amphotericin B and voriconazole.