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Langerhans cell histiocytosis of the optic chiasm
Author(s) -
Gangwani Vinod,
Walker Mark,
ElDefrawy Hany,
Nicoll James AR,
Reck Anne,
Pathmanathan Thillainathan
Publication year - 2007
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/j.1442-9071.2007.01418.x
Subject(s) - langerhans cell histiocytosis , medicine , histiocyte , optic chiasm , histiocytosis , limiting , pathology , visual disturbance , dermatology , rare disease , disease , optic nerve , anatomy , surgery , mechanical engineering , engineering
A bstract Langerhans cell histiocytosis (LCH) is a rare disease with clonal proliferation of dendritic histiocytes forming a pseudotumoral growth. LCH occurs most frequently in infancy or early childhood. It can present either as a localized self‐limiting form or as a diffuse form with multisystem involvement. Herein an unusual case of LCH involving the optic chiasm is presented. To the authors’ knowledge, this is the first reported case of LCH presenting with visual disturbance. The clinical, radiological and histopathological findings are discussed.