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Successful treatment of surgically induced necrotizing scleritis with tacrolimus
Author(s) -
Young Alvin L,
Wong SM,
Leung Alfred TS,
Leung Gloria YS,
Cheng Lulu L,
Lam Dennis SC
Publication year - 2005
Publication title -
clinical and experimental ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 1442-6404
DOI - 10.1111/j.1442-9071.2005.00955.x
Subject(s) - medicine , tacrolimus , dermatology , scleritis , surgery , ophthalmology , transplantation , uveitis
A 46‐year‐old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophosphamide and azathioprine, the scleral patch grafts failed within 1 month of surgery on both occasions. Tacrolimus was used for his third scleral patch graft. No recurrence of necrotizing scleritis was observed for 2 years. Tacrolimus may be considered as a valuable adjunctive immunosuppressant in the management of resistant necrotizing scleritis.