Open AccessA randomised prospective study of outpatient haemodilution for central retinal vein obstruction
Author(s) -
Luckie Alan P.,
Wroblewski John J.,
Hamilton Peter,
Bird Alan C.,
Sanders Michael,
Slater Nicolas,
Green William
Publication year - 1996
Publication title -
australian and new zealand journal of ophthalmology
Language(s) - English
Resource type - Journals
eISSN - 1440-1606
pISSN - 0814-9763
DOI - 10.1111/j.1442-9071.1996.tb01584.x
Subject(s) - medicine , visual acuity , incidence (geometry) , ophthalmology , central retinal vein occlusion , prospective cohort study , regimen , surgery , anesthesia , macular edema , physics , optics
Purpose: Central retinal vein obstruction (CRVO) has significant visual morbidity. We prospectively evaluated an outpatient haemodilution (HD) regimen for CRVO. Methods: We recruited 59 patients with CRVO of less than three months' duration and visual acuity (VA) worse than or equal to 6/9.5. Thirty patients underwent HD (packed cell volume of <0.35, 12 weeks); there were 29 controls and follow‐up was for six months. Results: Incidence rates for VA improvement ( P =0.708) and rubeosis iridis ( P =0.619) between the two groups were not different. The incidence rate of VA deterioration was 5.315 times higher with HD ( P =0.035, Cox Proportional analysis). Conclusion: This data does not support the previous studies on haemodilution.