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TRANSPLANTATION ANTIGENS AND KERATOPLASTY
Author(s) -
STARK WALTER J.,
TAYLOR HUGH R.,
DATILES MANUEL,
YOUNG ELAINE,
KLEIN PAMELA
Publication year - 1983
Publication title -
australian journal of opthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.3
H-Index - 74
eISSN - 1442-9071
pISSN - 0310-1177
DOI - 10.1111/j.1442-9071.1983.tb01102.x
Subject(s) - histocompatibility , corneal transplantation , human leukocyte antigen , cornea , histocompatibility testing , medicine , antigen , transplantation , immunology , corneal transplant , minor histocompatibility antigen , graft rejection , major histocompatibility complex , ophthalmology , surgery
Allograft rejection is one of the leading causes of corneal graft failure in man when the cornea is heavily vascularised. This paper reports the feasibility and possible benefits of using histocompatibility (HLA) antigen crossmatch testing and HLA‐D locus antigen matching for corneal donor selection. Double‐masked clinical trials designed to determine the value of these procedures for keratoplasty are discussed.