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Recurrent rhabdomyosarcoma after adjuvant chemotherapy for stage I non‐seminomatous germ cell tumor with malignant transformation
Author(s) -
Ushida Hiroshi,
Koizumi Shuichi,
Katoh Kenjiro,
Okabe Hidetoshi,
Okada Yusaku,
Okamoto Keisei
Publication year - 2013
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2012.03197.x
Subject(s) - medicine , etoposide , bleomycin , malignant transformation , embryonal rhabdomyosarcoma , germ cell , rhabdomyosarcoma , chemotherapy , germ cell tumors , cisplatin , teratoma , metastasis , orchiectomy , stage (stratigraphy) , adjuvant chemotherapy , oncology , adjuvant , pathology , cancer , sarcoma , biology , paleontology , biochemistry , breast cancer , gene
We report a rare case of stage I non‐seminomatous testicular germ cell tumor with malignant transformation. The patient received two cycles of chemotherapy (cisplatin, bleomycin and etoposide) tailored to testicular germ cell tumors as an adjuvant therapy after orchiectomy. However, 22 months later, the patient developed a metastasis in the occipital region that consisted of solely rhabdomyosarcoma through malignant transformation of a teratoma component. This case highlights an issue related to adjuvant chemotherapy for testicular germ cell tumors with components of malignant transformation.