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High‐grade invasive urothelial carcinoma with focal plasmacytoid differentiation successfully treated by transurethral resection followed by chemoradiotherapy
Author(s) -
Kawahara Takashi,
Oshiro Hisashi,
Sekiguchi Zenkichi,
Ito Hiroki,
Makiyama Kazuhide,
Uemura Hiroji,
Kubota Yoshinobu
Publication year - 2011
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2011.02880.x
Subject(s) - medicine , cystoscopy , nedaplatin , gemcitabine , bladder cancer , urology , urinary bladder , resection , chemotherapy , radiation therapy , urinary system , radiology , cancer , surgery , cisplatin
We report a case of high‐grade invasive urothelial carcinoma with plasmacytoid differentiation of the urinary bladder. A 75‐year‐old woman was referred to our hospital because of macroscopic hematuria. Cystoscopy detected a solid pedunculated bladder tumor, and a transurethral resection of the bladder tumor (TUR‐Bt) and the image findings showed pT1N0M0 bladder cancer. The histopathological examination revealed the coexistence of a large component of high‐grade invasive urothelial carcinoma and a small component of plasmacytoid carcinoma. Following the TUR‐Bt, external beam radiotherapy and chemotherapy with gemcitabine and nedaplatin were carried out. The bladder tumor has not recurred for 2 years after the TUR‐Bt.