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Photoselective vaporization of the prostate: Outcome according to the prostate size in a series of 102 Japanese patients
Author(s) -
Nomura Hiroyuki,
Seki Narihito,
Yamaguchi Akito,
Naito Seiji
Publication year - 2009
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2008.02184.x
Subject(s) - medicine , prostate , urology , international prostate symptom score , prospective cohort study , incidence (geometry) , lower urinary tract symptoms , cancer , physics , optics
Objectives: To identify the efficacy and safety of photoselective vaporization of the prostate (PVP) in relation to the prostate size in subjects with benign prostatic enlargement. Methods: The prospective study included 102 Japanese patients who underwent PVP. The efficacy and morbidity following PVP were compared in groups classified according to the baseline prostate size: prostates <40 cm 3 (group 1, n = 25), 40 cm 3 ≤ prostates <80 cm 3 (group 2, n = 53), and 80 cm 3 ≤ prostates (group 3, n = 24). Each subgroup was assessed for the treatment efficacy in terms of peak urinary flow rate, post‐void residual urine volume, International Prostate Symptom Score, and quality‐of‐life score at 3, 6 and 12 months after PVP. Results: Except for a difference in International Prostate Symptom Score (group 2 vs 3) and peak urinary flow rate (groups 1 vs 3) at 6 months after PVP, no significant differences were observed among the groups in the level of improvement in each outcome variable. The efficacy of vaporization was significantly lower in group 1 ( P < 0.05, group 1 vs 2 or 3). The hemoglobin loss after PVP did not differ substantially among the groups. No statistically significant difference was found among the three groups regarding the total incidence of adverse events. Conclusions: PVP appears to be a safe and effective treatment for benign prostatic enlargement, irrespective of the prostate size.