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Granular cell tumor of the urethra
Author(s) -
Yokoyama Hitoshi,
Kontani Kazuhiko,
Komiyama Itsuki,
Yoneyama Takehisa,
Nakazawa Kou
Publication year - 2007
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2007.01759.x
Subject(s) - medicine , granular cell tumor , enolase , vimentin , immunohistochemistry , eosinophilic , cytoplasm , pathology , biopsy , staining , urethra , transitional cell , positive staining , anatomy , transitional cell carcinoma , biology , cancer , bladder cancer , biochemistry
Abstract: A 38‐year‐old woman was referred for urethral tumor treatment. Needle biopsy of the tumor was performed. Histologically, the tumor was composed of large polygonal cells with eosinophilic and periodic acid‐Schiff (PAS)‐positive granular cytoplasm, indistinct cell margins and small round central nuclei. Immunohistochemical staining for S100 protein, vimentin, and neuron‐specific enolase (NSE) was positive, indicating that it was a granular cell tumor. Excision of the tumor including the urethra and appendicovesicostomy using the Mitrofanoff principle were performed. There has been no tumor recurrence in the 8 months after the operation.