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Collecting duct carcinoma producing granulocyte‐colony‐stimulating factor (G‐CSF)
Author(s) -
Sugiura Shimpei,
Makiyama Kazuhide,
Nakaigawa Noboru,
Yao Masahiro,
Kubota Yoshinobu,
Oshiro Hisashi
Publication year - 2007
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01711.x
Subject(s) - medicine , nedaplatin , leukocytosis , gemcitabine , chemotherapy , granulocyte colony stimulating factor , radiology , carcinoma , pathology , cisplatin
We present a 67‐year‐old male with a rare case of collecting duct carcinoma producing granulocyte colony‐stimulating factor. He was referred to us with lumbago and fever. Laboratory testing showed leukocytosis and computed tomography revealed a left renal mass. After chemotherapy with gemcitabine and nedaplatin, computed tomography showed a partial response. A left nephroureterectomy was performed. The histopathological diagnosis was collecting duct carcinoma producing granulocyte‐colony‐stimulating factor. White blood cell levels were reduced to 9900/mm 3 . No recurrence was detected after completion of adjuvant chemotherapy and the patient was discharged from the hospital. However, 3 months later, computed tomography revealed multiple lung metastasis. Nedaplatin‐ based chemotherapy was administered but computed tomography after chemotherapy identified a progressive disease. The patient died 9 months after the operation.