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Proximal‐type epithelioid sarcoma of the perineum: Calling attention of urologists
Author(s) -
HIKOSAKA ATSUYA,
YAMADA KENJI,
FUJITA KEIJI,
IWASE YUTAKA,
TADA TOYOHIRO
Publication year - 2006
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01581.x
Subject(s) - epithelioid sarcoma , medicine , vimentin , sarcoma , perineum , cd34 , pathology , metastasis , sarcomatoid carcinoma , carcinoma , anatomy , cancer , immunohistochemistry , biology , genetics , stem cell
A subcutaneous mass in the perineum of a middle‐aged man was excised and pathologically diagnosed at first as ‘undifferentiated carcinoma’ of unknown origin, which recurred 2 years later without any metastasis. Further histological evaluation ultimately established a correct diagnosis of ‘proximal‐type epithelioid sarcoma’, a variant of rare epithelioid sarcoma. This type of tumor may confuse pathologists because its histological characteristics resemble undifferentiated carcinoma or malignant rhabdoid tumor. Frequent immunoreactivity of CD34, in addition to expression of keratins, epithelial membrane antigen and vimentin, provides strong support for the diagnosis of this rare neoplasm. Urologists should be aware that this sarcoma commonly occurs in the genital regions.