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Granulomatous balanoposthitis after intravesical Bacillus‐Calmette‐Guerin instillation therapy
Author(s) -
YUSUKE HATTORI,
YOSHINORI HARA,
KENICHI MATSUURA,
AKIO HASEGAWA
Publication year - 2006
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01553.x
Subject(s) - foreskin , medicine , glans , penile cancer , glans penis , inguinal lymphadenopathy , balanitis , penis , surgery , urology , bladder cancer , biopsy , scrotum , cancer , pathology , genetics , biology , cell culture
We report a rare case of granulomatous balanoposthitis after intravesical Bacillus‐Calmette‐Guerin (BCG) instillation therapy in a 58‐year‐old man, which followed transurethral resection (TUR) for recurrent bladder cancer, when his anterior urethra was slightly narrow and his foreskin was with phimosis. Intravesical BCG instillation therapy was started for prophylaxis of recurrent bladder cancer after TUR. Multiple painless firm papules on glans penis, edema in the foreskin and low‐grade fever appeared after the seventh instillation, for which the single antituberculous agent isoniazid (300 mg/day) was administered. Biopsy of the papules on glans penis and foreskin revealed granulomatous balanoposthitis. Low‐grade fever normalized and the papules disappeared within 1 week. The patient continued chemotherapy with isoniazid for the next 12 months. There was no recurrence of bladder cancer or balanoposthitis for 15 months and to date.