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Papillary renal cell carcinoma: A clinicopathological study of 35 cases
Author(s) -
YAMANAKA KAZUKI,
MIYAKE HIDEAKI,
HARA ISAO,
INOUE TAKAAKI,
HANIOKA KEISUKE,
FUJISAWA MASATO
Publication year - 2006
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01500.x
Subject(s) - medicine , pathological , renal cell carcinoma , stage (stratigraphy) , incidence (geometry) , papillary carcinoma , papillary renal cell carcinomas , clear cell , carcinoma , metastasis , pathology , gastroenterology , cancer , thyroid carcinoma , thyroid , paleontology , physics , optics , biology
Aim: The objective of the present study was to characterize the clinicopathological features of histologically defined papillary renal cell carcinoma (RCC). Methods: The present study included a total of 35 patients who were treated by radical surgery and subsequently diagnosed as having papillary RCC between April 1995 and June 2004. Clinicopathological data of these patients were retrospectively reviewed according to the previously reported classification system (Mod. Pathol. 1997; 10: 537–44). Results: Of these 35 patients, 23 (65.7%) and 12 (34.3%) were diagnosed as type 1 and type 2 papillary RCC, respectively. Despite the lack of significant differences in clinical parameters between these two groups, including age, gender, clinical stage and metastasis, the incidence of symptomatic disease in patients with type 2 papillary RCC was significantly higher than that in those with type 1 papillary RCC. Pathological examinations demonstrated that there were no significant differences between these two groups in pathological stage, tumor grade or vascular invasion. Furthermore, there was no significant difference between these two groups in overall or recurrence‐free survival. Conclusions: Although the present study included a small number of patients with short follow‐up period, the clinicopathological features including prognoses were almost similar between patients with type 1 and type 2 papillary RCC; therefore, careful postoperative follow‐up should be considered for patients with papillary RCC irrespective of morphological subtype.