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Significant relationship of time‐dependent uroflowmetric parameters to lower urinary tract symptoms as measured by the International Prostate Symptom Score
Author(s) -
ITOH HIDEAKI,
KOJIMA MUNEKADO,
OKIHARA KOJI,
UKIMURA OSAMU,
USHIJIMA SO,
KAWAUCHI AKIHIRO,
MIKI TSUNEHARU
Publication year - 2006
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01496.x
Subject(s) - medicine , lower urinary tract symptoms , international prostate symptom score , prostate , urinary system , urology , cancer
Aims: The aim of the present paper is to elucidate the possible involvement of time‐dependent parameters as obtained by uroowmetry in the manifestation of lower urinary tract symptoms (LUTS) in elderly patients. Methods: Using simple and multiple regression analyses, the correlation of the International Prostate Symptom Score (IPSS) with objective parameters including age, postvoid residual, uroowmetry and transrectal ultrasonic measurements of the prostate was analyzed in 206 male patients (average age of 68.0 ± 7.4 years) who visited our outpatient clinic complaining of LUTS. Results: In the 206 patients, the mean maximum ow rate was 12.2 mL/s (13.7 mL/s in mild, 11.9 mL/s in moderate, and 11.2 mL/s in severe IPSS total score) and average ow rate was 4.4 mL/s (5.4 mL/s in mild, 4.3 mL/s in moderate, and 3.5 mL/s in severe IPSS total score). Simple regression analyses demonstrated that age, voiding time, and average and maximum ow rates correlate significantly with symptom scores. In particular, relatively strong relationships were found between average ow rate and scores of intermittency, weak stream and total and voiding symptoms scores. Serum prostate specific antigen level, postvoid residual and prostatic ultrasonic measurements did not show a significant correlation with symptom scores. Multiple regression analyses revealed age and average ow rate to be independent determinants for symptom scores. Conclusion: These results suggest that the time‐dependent function in micturition interferes in the manifestation of LUTS in elderly men who have borderline or pathologic maximum ow rate. When evaluating uroowmetry in elderly male patients with LUTS, attention should be paid to time‐dependent parameters such as voiding time and average ow rate.