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Baseline health‐related quality of life in the management of prostate cancer
Author(s) -
ISHIHARA MASAHARU,
SUZUKI HIROYOSHI,
AKAKURA KOICHIRO,
KOMIYA AKIRA,
IMAMOTO TAKASHI,
TOBE TOYOFUSA,
ICHIKAWA TOMOHIKO
Publication year - 2006
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01441.x
Subject(s) - medicine , prostate cancer , quality of life (healthcare) , prostate , prospective cohort study , sexual function , cohort , cancer , stage (stratigraphy) , health related quality of life , biopsy , disease , oncology , gynecology , paleontology , nursing , biology
Objectives: The purpose of this study was to clarify characteristics of baseline health‐related quality of life (HRQOL) during the diagnostic process of prostate cancer. Methods: A prospective study was conducted to measure HRQOL in a cohort of 141 patients in whom prostate cancer was suspected and prostate biopsy was scheduled, using both generic and disease‐specific HRQOL measures (SF‐36, UCLA‐Prostate Cancer Index) at two points: before prostate biopsy (prediagnosis) and after giving biopsy results (postdiagnosis). Seventy‐three patients were diagnosed with prostate cancer and 68 were not. Results: Compared to age‐gender adjusted population norms, patients demonstrated better physical function (PF) and worse mental health (MH). Characteristic age‐related changes were found in PF and sexual function (SXF); however, disease stage exhibited no relevant effects in HRQOL. No significant difference was detected between pre‐ and postdiagnosis SF‐36 and UCLA‐PCI scores. Conclusion: The present study discovered no relevant impact of the diagnostic process of prostate cancer on baseline HRQOL using SF‐36 and UCLA‐PCI. Combined with results of previous studies, it is supportive of regarding pretreatment levels of HRQOL as the baseline.