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Transient anuria requiring nephrostomy after intravesical bacillus Calmette‐Guérin instillations for superficial bladder cancer
Author(s) -
KANEKO TOMOYUKI,
FUJITA KIICHIRO,
HOMMA YUKIO
Publication year - 2006
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2006.01283.x
Subject(s) - medicine , anuria , percutaneous nephrostomy , nephrostomy , urology , bladder cancer , hydronephrosis , transitional cell carcinoma , surgery , urinary system , percutaneous , cancer
A 76‐year‐old man received intravesical bacillus Calmette‐Guérin (BCG) instillations for recurrent superficial bladder cancer. He had undergone right nephroureterectomy for right renal pelvic cancer 9 months previously. He presented with anuria and left hydronephrosis after the fourth instillation, with serum creatinine increasing up to 15.7 mg/dL. Percutaneous nephrostomy was indwelled, and antegrade pyelography showed left vesicoureteral obstruction. There was no sign of recurrent bladder cancer or ureteral cancer. He started spontaneous voiding on day 4 and the nephrostomy was removed on day 8. Most of the side‐effects of intravesical BCG therapy are minor, and major adverse reactions are rare. Life‐threatening ureteral obstruction would be a rare complication of BCG immunotherapy. Although BCG intravesical instillation after nephroureterectomy is a common practice, special care should be taken of renal function in patients with unilateral kidney during BCG therapy.