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Synchronous anal and penile cancers
Author(s) -
WYSOCKI WOJCIECH M,
KOMOROWSKI ANDRZEJ L,
KOLODZIEJSKI LESZEK S,
WYSOCKA JOANNA
Publication year - 2004
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2004.00955.x
Subject(s) - medicine , penile cancer , foreskin , anus , anal cancer , lesion , lichen sclerosus , pathology , dermatology , koilocyte , hyperkeratosis , penis , acanthosis , etiology , cancer , precancerous lesion , cervical cancer , anatomy , biology , cervical intraepithelial neoplasia , genetics , cell culture
Malignancies of the anogenital region have similar etiology, including viral infections, sexual habits, social and educational factors. Condylomata acuminata represent precancerous lesions. In the available literature, we found no cases of synchronous cancers of anus and penis reported. We report a case of synchronous cancer of the penile foreskin and cancer of the anus in a 36 year‐old man. The microscopic diagnosis of the anal lesion was squamous cell cancer, basaloid type. The penile lesion was squamous cell cancer, keratinizing type. Both cancers presented with the in situ component. Immunohistochemical staining (MIB‐1) and histological features (koilocytosis, acanthosis and dyskeratosis) indirectly confirmed the past viral infection. Numerous etiological similarities in anogenital cancers entail careful clinical inspection in patients with a malignant lesion in this region and suggest searching for possible other concomitant cancers or precancerous lesions.