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Interstitial pneumonitis related to flutamide monotherapy for prostate cancer
Author(s) -
NOMURA MASAYOSHI,
SATO HIDEKI,
FUJIMOTO NAOHIRO,
MATSUMOTO TETSURO
Publication year - 2004
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2004.00882.x
Subject(s) - flutamide , medicine , prostate cancer , urology , prostate , interstitial pneumonitis , enzalutamide , pneumonitis , antiandrogen , combination therapy , cancer , radiation therapy , oncology , lung , respiratory disease , androgen receptor
A 88‐year‐old man with prostate cancer was receiving non‐steroidal anti‐androgen therapy (flutamide, 375 mg/day). Three weeks after starting therapy, the patient developed dyspnea and bilateral pulmonary interstitial infiltrates. The withdrawal of flutamide and the initiation of steroid therapy resulted in clinical improvement.