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Successful treatment for squamous cell carcinoma of the female urethra with combined radio‐ and chemotherapy
Author(s) -
HARA ISAO,
HIKOSAKA SATOKO,
ETO HIROSHI,
MIYAKE HIDEAKI,
YAMADA YUJI,
SOEJIMA TOSHINORI,
SUGIMURA KAZURO,
KAMIDONO SADAO
Publication year - 2004
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.2004.00859.x
Subject(s) - medicine , urethra , chemotherapy , cisplatin , radiation therapy , metastasis , lymph node , basal cell , lymph , carcinoma , surgery , urology , cancer , pathology
We report on two cases of women with locally advanced squamous cell carcinoma of the urethra. Patient 1 also displayed regional lymph node metastasis. Treatment comprised combined radiotherapy to 60 Gy and chemotherapy with 5‐fluorouracil and cisplatin. Complete response was obtained in both patients, including the inguinal lymph nodes of Patient 1. Patient 1 experienced recurrent inguinal lymph node metastasis on the contralateral side at 42 months after initial treatment, and the same treatment was performed followed by surgical excision. Both patients remain alive with no evidence of disease, at 12 months after recurrence in Patient 1, and at 27 months after treatment in Patient 2.