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long‐term Follow‐up Study of Penile Cancer
Author(s) -
Yamada Yuji,
Gohji Kazuo,
Hara Isao,
Sugiyama Takeki,
Arakawa Soichi,
Kamidono Sadao
Publication year - 1998
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.1998.tb00598.x
Subject(s) - medicine , penile cancer , lymphadenectomy , stage (stratigraphy) , multivariate analysis , lymph node , cancer , lymph , oncology , surgery , urology , pathology , paleontology , biology
Background: We reviewed the outcomes for patients with penile cancer to determine factors predictive of their survival. Methods: Between 1966 and 1996, 59 patients with penile cancer were treated at Kobe University Hospital. The median follow‐up period was 109 months (range, 4 to 240 months). The prognostic factors were determined by multivariate analysis. Disease progression rates, according to stage and the type of surgery, were studied. Results: The 5‐and 10‐year, cause‐specific survival rates were 75.9|X% and 73.8|X%, respectively. Lymph node involvement, tumor stage, and tumor differentiation were the independent risk factors identified by multivariate analysis. Among the patients at stage 1 and 2, none of the 29 patients treated with early lymphadenectomy showed recurrence in the inguinal region, while 4 (27|X%) of 15 patients without lymphadenectomy showed such recurrence. Conclusion: Our results suggestthattumor stage, lymph node involvement, and tumor differentiation are significant prognostic factors for survival, and that early inguinal lymphadenectomy would improve the prognosis of patients with stage 1 or 2 penile cancer.