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Pros‐Eight TM Transurethral Radiofrequency Thermotherapy for Benign Prostatic Hyperplasia: Preliminary Clinical Results
Author(s) -
Yoshida Osamu,
Terai Akito,
Shichiri Yasumasa,
Okada Yusaku,
Ishitoya Satoshi,
Okubo Kazutoshi,
Suzuki Yuji,
Arai Yoichi
Publication year - 1996
Publication title -
international journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 67
eISSN - 1442-2042
pISSN - 0919-8172
DOI - 10.1111/j.1442-2042.1996.tb00575.x
Subject(s) - medicine , hyperplasia , urology , prostate , international prostate symptom score , lower urinary tract symptoms , prostatic urethra , urethra , surgery , cancer
Background: We have developed a new transurethral thermotherapy device using 8MHz radiofrequency (RF) for the treatment of patients with symptomatic benign prostatic hyperplasia (BPH). We report the safety and effectiveness of the initial clinical experience with this device Methods: Sixty patients with symptomatic BPH were subjected to a single 1‐hour treatment under local anesthesia. The treatment device uses extracorporeal RF capacitive heating in combination with radiative heating and conductive cooling of the urethra. Results: In the 49 patients evaluahle at 3 months, the mean International Prostate Symptom Score decreased from 17.8 to 13.1 ( P < 0.0001) and the Quality of Life score decreased from 4.4 to 3.4 (P < 0.0005). Maximum flow rate increased from 8.1 to 9.7mL/s (P< 0.05) at 3 months. Overall effectiveness by Homma's response criteria was as follows; excellent 4.1%, good 10.2%, fair 38.8% and poor 46.9%. Side effects were minimal. Gross hematuria was seen in 3 patients and erosion of the external urethral meatus was seen in 2 patients, but none had urinary retention. Conclusions: In this initial clinical trial, transurethral RF thermotherapy was safe and resulted in modest symptomatic improvement. Further investigations for optimizing the treatment protocol seem warranted.