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Characteristic alteration in the second derivative of photoplethysmogram in children
Author(s) -
Hasegawa Satoshi,
Sato Seiichi,
Numano Fujito,
Park Jiksoo,
Hoshina Satoshi,
Endoh Hikosato,
Suzuki Hiroshi,
Uchiyama Makoto
Publication year - 2011
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.2010.03235.x
Subject(s) - medicine , photoplethysmogram , dipyridamole , cardiology , gastroenterology , filter (signal processing) , computer science , computer vision
Background: The second derivative of the photoplethysmogram (SDPTG) has been verified as a useful method for analyzing pulse wave form in adults; however, there have been few studies on the SDPTG in children. Methods: We examined age‐related alteration of SDPTG (study 1) and the SDPTG response to a vasodilator (study 2). The subjects in study 1 were 36 healthy children aged 0.9–16.0 years. The subjects in study 2 were 13 children aged 5.4–18.9 years with a history of Kawasaki disease. Subjects received an i.v. infusion of 0.568 mg/kg dipyridamole. We assessed the SDPTG by d/a ratio, b/a ratio and aging index (AGI). Results: The d/a ratio increased with advance of age ( r = 0.636, P < 0.001), and the b/a ratio and AGI decreased with advance of age ( r =−0.343, P < 0.05 and r =−0.678, P < 0.001, respectively). The d/a ratio and AGI were correlated with height ( r = 0.523, P < 0.01 and r =−0.623, P < 0.001, respectively), but the b/a ratio was not significantly correlated with height. In study 2, the d/a ratio increased significantly ( P ≤ 0.05), but the b/a ratio and AGI did not alter. Conclusions: The SDPTG indices in children show characteristic alterations with advance of age and react to a vasodilator.