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High prevalence of antibodies against Bartonella henselae with cervical lymphadenopathy in children
Author(s) -
Asano Takeshi,
Ichiki Kunihiko,
Koizumi Shinya,
Kaizu Kiyohiko,
Hatori Takayuki,
Fujino Osamu
Publication year - 2010
Publication title -
pediatrics international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.49
H-Index - 63
eISSN - 1442-200X
pISSN - 1328-8067
DOI - 10.1111/j.1442-200x.2010.03066.x
Subject(s) - bartonella henselae , medicine , cat scratch disease , cervical lymphadenopathy , serology , bartonella , kawasaki disease , bartonellosis , etiology , antibody , immunology , disease , virology , pathology , artery
Background: Cat‐scratch disease is the most common form of Bartonella henselae infection. Although reports have shown that CSD is relatively common, they have not shown the prevalence of seropositivity for Bartonella henselae in cases of cervical lymphadenitis and Kawasaki disease, which are relatively common diseases in children. Methods: We evaluated the presence of immunoglobulin (Ig) G‐ and IgM‐class antibodies against Bartonella henselae in children with cervical lymphadenitis, Kawasaki disease, and infectious diseases without lymphadenopathy in a semi‐rural area in Japan. Results: We found that the positivity rate for the IgG antibody against Bartonella henselae in patients with cervical lymphadenitis who owned cats or dogs was significantly higher than that in patients with Kawasaki disease and infectious diseases without lymphadenopathy. However, the average age of children with cervical lymphadenitis did not significantly differ when compared to those with other infectious diseases. Conclusion: Our serological study showed that Bartonella henselae infection may contribute to the etiology of cervical lymphadenitis in children.